Table 1 Current enzyme reaction rules

1

ManI

[3.2.1.113]

(Ma2Ma

(Ma

\(\thicksim \)*2Ma3(...Ma6)

2

ManI

[3.2.1.113]

(Ma3(Ma2Ma3(Ma6)Ma6)

(Ma3(Ma3(Ma6)Ma6)

3

ManII

[3.2.1.114]

(Ma3(Ma6)Ma6

(Ma6Ma6

(GNb2 |Ma3 & \(\thicksim \)Gnbis)

4

ManII

[3.2.1.114]

(Ma6Ma6

(Ma6

(GNb2 |Ma3 & \(\thicksim \)Gnbis)

5

FUT8

[2.4.1.68]

GNb4GN

GNb4(Fa6)GN

GNb2 |Ma3 & \(\thicksim \)Gnbis & \(\thicksim \)Ab

6

MGAT1

[2.4.1.101]

(Ma33(Ma3(Ma6)Ma6)Mb4

(GNb2Ma3(Ma3(Ma6)Ma6)Mb4

7

MGAT2

[2.4.1.143]

(GNb2|Ma3(Ma6)Mb4

(GNb2 |Ma3(GNb2Ma6)Mb4

8

MGAT3

[2.4.1.144]

GNb2 |Ma3

GNb2 |Ma3(GNb4)

\(\thicksim \)Ab & \(\thicksim \)Gnbis

9

MGAT4

[2.4.1.145]

(GNb2Ma3

(GNb2(GNb4)Ma3

\(\thicksim \)Gnbis

10

MGAT5

[2.4.1.155]

(GNb2Ma6

(GNb2(GNb6)Ma6

\(\thicksim \)Gnbis

11

iGnT

[2.4.1.149]

(Ab4GN

(GNb3Ab4GN

\(\thicksim \)_Ma3 |Mb4

12

b4GalT

[2.4.1.38]

(GN

(Ab4GN

(\(\thicksim \)*GNb4)(…Ma6)Mb4

13

a3SiaT

[2.4.99.6]

(Ab4GN

(NNa3Ab4GN

14

IGNT

[2.4.1.150]

(Ab4GNb3Ab

(Ab4GNb3(GNb6)Ab

15

a6SiaT

[2.4.99.1]

(Ab4GN

(NNa6Ab4GN

16

b3GalT1

[2.4.1.62]

(GN

(Ab3GN

(\(\thicksim \)*GNb4)(…Ma6)Mb4

17

FUT3

[2.4.1.65]

Ab3GNb

Ab3(Fa4)GNb

(Ab3* or (Fa2Ab3* or (NNa3Ab3*)

18

FUT3

[2.4.1.65]

(…Ab4GNb

(Fa3(…Ab4)GNb

(*Ab4 or (*Fa2Ab4 or (*NNa3Ab4)

19

FUT1

[2.4.1.69]

(Ab3GNb

(Fa2Ab3GNb

20

FUT1

[2.4.1.69]

(Ab4GNb

(Fa2Ab4GNb

21

a3FucT

[2.4.1.152]

(…Ab4GNb

(Fa3(…Ab4)GNb

(*Ab4 or (*Fa2Ab4

22

GalNAcT-A

[2.4.1.40]

(Fa2Ab

(Fa2(ANa3)Ab

23

GalT-B

[2.4.1.37]

(Fa2Ab

(Fa2(Aa3)Ab

24

b3GALT6

[2.4.1.134]

Ab4GN

Ab3Ab4GN

25

b3GALT6

[2.4.1.134]

Ab4A

Ab3Ab4A

26

c1GALT1

[2.4.1.122]

AN

Ab3AN

27

st3galI

[2.4.99.4]

(Ab3GN

(NNa3Ab4GN