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Fig. 1 | BMC Bioinformatics

Fig. 1

From: tarSVM: Improving the accuracy of variant calls derived from microfluidic PCR-based targeted next generation sequencing using a support vector machine

Fig. 1

Sensitivity of detecting variant sites in exome chip dataset of 373 subjects. Panel (a) shows the sensitivity of detecting sites (N = 202) an allele count greater than one in the Exome Chip dataset of 373 subjects using microfluidic PCR for the same subjects. Panel (b) shows a similar sensitivity analysis, except it is limited to sites with an allele count of exactly one (N = 61). Please note that the “No Filter” bar is an upper bound for all methods except GotCloud SVM. The overall conclusion from these two plots is that tarSVM’s sensitivity is very close to the most sensitive methods for common and rare variants

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