Fig. 4
From: Assessment of transfer methods for comparative genomics of regulatory networks in bacteria
Assessment of IC (left) and Gini coefficient (right) as predictive indices of accuracy for network-based transfer methods. The plots show the distribution of PR-AUC from bidirectional transfers between 179 TF-specific species pairs using network transfer (ortholog mode), with respect to each index. PR-AUC values are normalized to the respective AUC of the known target TF-binding motif to compensate for the decreased search efficiency of low information content motifs. IC and Gini coefficient values are normalized to those observed on the known reference motif. The dotted vertical line designates 0.5 normalized motif IC/Gini. The dotted horizontal line identifies the PR-AUC value (0.056) two standard deviations above the mean obtained from simulated transfers with permuted motifs.