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Table 2 Distribution of peptide-HLA targets with respect to the genes from which the peptides are derived. The number of unique peptide-HLA targets derived from each gene is also listed

From: In-silico discovery of cancer-specific peptide-HLA complexes for targeted therapy

 

Gene

Count

Unq.count

1

MAGEA3

84

12

2

MAGEA6

70

10

3

UMODL1

54

54

4

MAGEA9B

52

13

5

NLRP4

47

47

6

MAGEA4

45

9

7

CNTNAP5

35

35

8

MAGEA12

32

16

9

RPE65

30

15

10

ANKRD30A

23

23

11

SMC1B

22

22

12

MAGEA1

22

11

13

MAGEC2

18

18

14

DNTT

16

16

15

TGM4

16

16

16

MAGEA11

13

13

17

TRIM51

11

11

18

DSCR8

10

5

19

EPYC

8

8

20

POTEM

7

7

21

COX7B2

5

5

22

C7orf72

4

4

23

MTRNR2L1

2

2

24

KLKP1

1

1

  1. Some genes provided targets that are specific to multiple cancer types, e.g., MAGEA3 provided 12 unique targets that are specific to 7 different cancer types, equivalent to 84 targets, in total, across 7 cancer types
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BMC Bioinformatics

ISSN: 1471-2105

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