Fig. 2

DISMISS predictions of the DNA strand on which the 5mC occurs are not influenced by read depth. a MACS2 peaks. The frequency of occurrence of peaks, with a certain depth of first mate reads, on the plus and minus strands. The minimum read depth is 12 first mate reads. b DISMISS peaks. The depth of first mate reads on the plus strand is plotted against the depth of first mate reads on the minus strand. The predictions made by DISMISS are indicated in grey scale and marked on the graph; they show well defined linear boundaries. The minimum read depth is 12 first mate reads