Fig. 3

The operation time consumption benchmark on the associations for ~250,000 CpGs and one environmental factor and one covariate for the sequential number of samples from 100 to 1000. X-axis is the number of subjects, and y-axis is the time consumption in seconds. The benchmarking is done in a personal computer (processor = 2.2GHz, RAM = 8G, system = window7 64bit)