Skip to main content

Table 3 Benchmarking time consumption of GEM implementations on Emodel, Gmodel and GxEmodel by comparing normal R script in a public available dataset in standard laptop and HPC settings

From: Gene, Environment and Methylation (GEM): a tool suite to efficiently navigate large scale epigenome wide association studies and integrate genotype and interaction between genotype and environment

 

Dataset: Teh et al., 1423 CpGs, 708,365 SNPs and 19 environments in a standard laptop

Method

Time cost on standard laptop

Time cost in HPC

Method

Time cost

LM_Emodel

95.1 s

 

GEM_Emodel

18.9 s

LM_Gmodel

> = 60 days (a)

3 h

GEM_Gmodel

5.2 min

LM_GxEmodel

> = 60 days (a)

21 h

GEM_GxEmodel

1.5 h

  1. aThe time for LM_Gmodel and LM_GxEmodel in standard laptop was computed based on the time cost on 10 CpGs