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Table 4 Comparison of performance in identifying FAD binding sites in the electron transport chain with different feature sets

From: Prediction of FAD binding sites in electron transport proteins according to efficient radial basis function networks and significant amino acid pairs

Feature set True positive False positive True negative False negative Sens Spec Acc MCC
BINARY 45 972 2058 18 71.43 67.92 67.99 0.12
BLOSUM62 41 977 2053 22 65.08 67.76 67.7 0.1
PAM250 42 996 2032 21 66.67 67.11 67.1 0.1
PSSM 51 1169 1861 12 80.95 61.42 61.82 0.12
PSSM + F-score 51 1142 1888 12 80.95 62.31 62.69 0.13
PSSM + SAAPs 54 1074 1955 9 85.71 64.54 64.97 0.15