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Fig. 3 | BMC Bioinformatics

Fig. 3

From: An ensemble framework for identifying essential proteins

Fig. 3

Performance comparison of five centrality measures (BC, CC, DC, EC, and SC) on two yeast PINs (PIN24K and PIN76K) using absolute thresholding strategy. For each yeast PIN (PIN24K or PIN76K), 15 PINs are generated by using the absolute thresholding strategy. Proteins are ranked according to their values calculated by each centrality measure on each PIN. For each centrality measure on each PIN, top n proteins are selected as candidates for essential proteins, out of which the number of true essential proteins are determined. The PIN with threshold 0 is the original PIN (PIN24K for (a)-(d), and PIN76K for (e) ~ (h)). X-axis represents the thresholds and y-axis the number of true essential proteins in top n ranked proteins. Proteins contained in standard-1122 are considered as essential proteins

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