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Table 3 Degree distribution characteristics among the top 100 proteins ranked by different centrality measures and different ensemble methods

From: An ensemble framework for identifying essential proteins

   BC EnBC-a CC EnCC-a DC EnDC-a EC EnEC-a SC EnSC-a
PIN76K Average degree 306.32 135.99 277.71 108.88 327.57 94.21 290.7 93.37 326.98 94.54
Minimal degree 17 10 24 6 138 20 83 23 127 20
#low_degree - 1 - 7 - 89 - 60 - 83
#EP - 0 - 2 - 75 - 52 - 69
Average node strength 0.07 0.42 0.08 0.47 0.12 0.57 0.2 0.58 0.2 0.54
PIN24K Average degree 93.23 37.63 89.96 26.51 97.11 25.44 79.14 21.43 97.04 24.82
Minimal degree 33 4 33 4 64 4 31 3 60 4
#low_degree - 62 - 76 - 95 - 78 - 93
#EP - 47 - 64 - 78 - 64 - 78
Average node strength 0.07 0.35 0.06 0.45 0.07 0.5 0.05 0.53 0.05 0.39
  1. #low_degree denotes the number of proteins out of the top 100 ranked proteins by an ensemble method whose degrees are less than the minimal degree of the top 100 proteins ranked by the corresponding centrality measure, and #EP the number of essential proteins out of the #low_degree proteins