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Fig. 3 | BMC Bioinformatics

Fig. 3

From: CloneCNA: detecting subclonal somatic copy number alterations in heterogeneous tumor samples from whole-exome sequencing data

Fig. 3

CNA detection performance of ExomeCNV, Control-FREEC, EXCAVATOR, THetA and CloneCNA on simulated heterogeneous samples. Sensitivity and specificity are calculated for each sample based on the results of each investigated method. a Results for samples containing two clonal populations. For the sample with tumor purity of 0.25, EXCAVATOR reports a running error, therefore the performance of EXCAVATOR and THetA on this sample is not evaluated. b Results for samples containing three clonal populations. c Results for samples containing four clonal populations

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