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Table 1 Copy number aberration states defined in CloneCNA

From: CloneCNA: detecting subclonal somatic copy number alterations in heterogeneous tumor samples from whole-exome sequencing data

Id

Total copy number

Major copy number

Tumor genotypes

Aberration type

1

0

0

N/A

HOMD

2

1

1

A, B

HEMD

3

2

1

AB

NHET

4

2

2

AA, BB

NLOH

5

3

2

AAB, ABB

AHET

6

3

3

AAA, BBB

ALOH

7

4

2

AABB

AHET

8

4

3

AAAB, ABBB

AHET

9

4

4

AAAA, BBBB

ALOH

10

5

3

AAABB, AABBB

AHET

11

5

4

AAAAB, ABBBB

AHET

12

5

5

AAAAA, BBBBB

ALOH

  1. Aberration types include homozygous deletion (HOMD), hemizygous deletion (HEMD), copy neutral heterozygosity (NHET), copy neutral LOH (NLOH), amplified heterozygosity (AHET) and amplified LOH (ALOH)