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Table 8 List of biological process GO terms significantly enriched and uniquely appearing in each topic for embryonic mouse cell differentiation

From: CellTree: an R/bioconductor package to infer the hierarchical structure of cell populations from single-cell RNA-seq data

GO.ID

Term

p-Value

Topic 1

GO:0032543

mitochondrial translation

2.2e-07

GO:0015031

protein transport

2.7e-07

GO:0015986

ATP synthesis coupled proton transport

1.8e-06

Topic 2

GO:0042254

ribosome biogenesis

7.1e-10

GO:0000462

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

7.2e-10

GO:0042273

ribosomal large subunit biogenesis

4.1e-08

Topic 3

GO:0007049

cell cycle

1.6e-09

GO:0045893

positive regulation of transcription, DNA-templated

1.5e-08

GO:0006355

regulation of transcription, DNA-templated

1.2e-07

GO:0000122

negative regulation of transcription from RNA polymerase II promoter

3.2e-07

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

5.5e-07

GO:0000281

mitotic cytokinesis

1.5e-06

Topic 4

GO:0055114

oxidation-reduction process

< 1e-30

GO:0006805

xenobiotic metabolic process

3.5e-13

GO:0042738

exogenous drug catabolic process

1.9e-12

GO:0006749

glutathione metabolic process

4.3e-12

GO:1901606

alpha-amino acid catabolic process

6.9e-10

GO:0046700

heterocycle catabolic process

9.8e-10

GO:0008203

cholesterol metabolic process

1.0e-09

GO:0019373

epoxygenase P450 pathway

7.6e-09

GO:0044270

cellular nitrogen compound catabolic process

1.0e-08

GO:0006958

complement activation, classical pathway

1.2e-08

GO:0006641

triglyceride metabolic process

4.2e-08

GO:0045454

cell redox homeostasis

4.4e-08

GO:0019439

aromatic compound catabolic process

6.0e-08

GO:1901361

organic cyclic compound catabolic process

7.3e-08

GO:0030433

ER-associated ubiquitin-dependent protein catabolic process

1.2e-07

GO:0006953

acute-phase response

1.4e-07

GO:0010951

negative regulation of endopeptidase activity

2.7e-07

GO:0042493

response to drug

5.4e-07

GO:0006103

2-oxoglutarate metabolic process

5.8e-07

GO:0042537

benzene-containing compound metabolic process

6.2e-07

GO:0010466

negative regulation of peptidase activity

9.0e-07

GO:0019748

secondary metabolic process

9.8e-07

GO:0006120

mitochondrial electron transport, NADH to ubiquinone

1.0e-06

GO:0042744

hydrogen peroxide catabolic process

1.0e-06

GO:0009813

flavonoid biosynthetic process

1.4e-06

GO:0052696

flavonoid glucuronidation

1.4e-06

GO:0046688

response to copper ion

1.5e-06