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Fig. 7 | BMC Bioinformatics

Fig. 7

From: Interpreting transcriptional changes using causal graphs: new methods and their practical utility on public networks

Fig. 7

This figure shows simulations results in recovering upstream regulators using the quaternary (blue), correctness (red) and ES (green) scoring statistics. Thin lines represent individual simulations and thick lines represent the averages across the 1000 simulations. The x-axis represents the percentage of ambiguous edges in the network and the y-axis represents the p-value on a log scale. Figure on the left depicts an active regulator R1 simulated to be up-regulated. Figure on the right depicts an inactive regulator R2 that shares downstream transcripts with R1 but has a different direction of regulation for 50 % of its edges. The dotted black line marks a significance level of 1e-5. Further details in the main text

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BMC Bioinformatics

ISSN: 1471-2105

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