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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Optimized pipeline of MuTect and GATK tools to improve the detection of somatic single nucleotide polymorphisms in whole-exome sequencing data

Fig. 2

The GATK-LODN method reduces the number of GATK false positive calls. Comparison of the number of SNVs between GATK and MuTect before (a) and after (b) applying the GATK-LODN method for each cancer whole exome sequencing dataset. AML: Acute Myeloid Leukemia, ALL: Acute Lymphoblastic Leukemia, GIST: Gastrointestinal Stromal Tumor, LA: Lung Adenocarcinoma

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