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Table 6 Data set STRING-CORE (homo sapiens). Functionally enriched clusters found with min size 8 and filtering policy 1

From: Protein complex prediction for large protein protein interaction networks with the Core&Peel method

GO annotation

Type

GO id

Clust. size

Inters.

Class size

Hyp. p-value

mRNA splicing, via spliceosome

BP

GO:0000398

91

90

183

8.23E–191

G2/M transition of mitotic cell cycle

BP

GO:0000086

52

52

121

5.62E–120

Mitotic cell cycle

BP

GO:0000278

68

68

384

6.24E–118

G-protein coupled receptor signaling pathway

BP

GO:0007186

126

97

918

1.16E–101

Type I interferon signaling pathway

BP

GO:0060337

33

33

65

4.48E–86

O-glycan processing

BP

GO:0016266

30

30

55

7.44E–81

Platelet degranulation

BP

GO:0002576

32

32

82

4.14E–79

Interferon-gamma-mediated signaling pathway

BP

GO:0060333

30

30

70

1.33E–76

Extracellular matrix organization

BP

GO:0030198

40

40

272

2.26E–75

Transferrin transport

BP

GO:0033572

24

24

32

2.40E–72

  1. We report the top ten clusters by hypergeometric p-value. Each row reports: the GO annotation class, GO class type (BP=Biological Process), the GO id, the size of the cluster, the size of the intersection, the size of the functional class, and the hypergeometric p-value