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Table 3 Multivariate Cox analysis results of the test set

From: Artificial neural network classifier predicts neuroblastoma patients’ outcome

 

Multivariate cox analysis (OS)a

Multivariate cox analysis (EFS)b

Covariate

Coefficientc

HRd

95 % Cle

P-valuef

Coefficientc

HRd

95 % Cle

P-valuef

NB-hypo classifier (Good vs Poor)

1.1

3.3

(1.0, 10.6)

4.00E-02

1.1

3

(1.0, 9.0)

4.00E-02

Age group (<12 months vs ≥ 12 months)

1.9

4E-08

(0.0, inf)

9.90E-01

1.2

3.6

(0.9, 14.2)

6.00E-02

INSS stage (1,2,3,4s vs 4)

0.6

1.9

(0.5, 6.4)

2.70E-01

0.4

1.5

(0.5, 4.5)

4.00E-04

MYCN status (nomal vs amplified)

0.3

1.3

(0.5, 3.5)

4.90E-01

0.4

1.5

(0.6, 3.9)

3.00E-01

  1. aMultivariate cox regression analysis for overall survival
  2. bMultivariate cox regression analysis for event - free survival
  3. cCox regression coefficient
  4. dHazard ratio
  5. e95 % of confidence interval
  6. fSignificance. Values smaller than 0.05 are acceptable