Table 2 For each top 6 pairwise pathway in luminal A: miRNA regulators of pathways, their expression levels in BC and in NS, and the statistical significance of the comparison (in terms of log Fold Change)
From: How interacting pathways are regulated by miRNAs in breast cancer subtypes
Pairwise pathways | miRNA-r | miRNA-r Exp. in BC | miRNA-r Exp. in NS | Statistical significance (log Fold Change) |
|---|---|---|---|---|
1. a) Acute Phase Response Signalling;   b) HIF1 Signalling | Hsa-miR-205 | 13006.16 | 25001.9 | -1.01017 |
2. a) Axonal Guidance Signalling;   b) Acute Phase Response Signalling | Hsa-miR-452 Hsa-miR-335 Hsa-miR-205 Hsa-miR-99a Hsa-miR-337 Hsa-miR-1250 | 101.1974 333.4506 13006.16 4268.871 208.6352 0.746781 | 720.023 1391.644 25001.9 10953.55 547.3908 0.103448 | -3.08782 -2.27528 -1.01017 -1.71181 -1.57547 1.636118 |
3. a) Ethanol Degradation IV;   b) Glioma Invasiveness Signalling | Hsa-miR-3199-1 | 1.793991 | 5.45977 | -1.79743 |
4. a) Ethanol Degradation IV;   b) Estrogen Receptor Signalling | Hsa-miR-1-1 | 0.021459 | 1.62069 | -3.82055 |
5. a) Glioma Invasiveness Signalling;   b) Oxidative Ethanol Degradation III | Hsa-miR-3199-1 | 1.793991 | 5.45977 | -1.79743 |
6. a) Extrinsic Prothrombin Activation;   b) Intrinsic Prothrombin Activation | Hsa-miR-1537 Hsa-miR-210 Hsa-miR-99a Hsa-miR-381 | 0.957082 1592.884 4268.871 138.0215 | 0.333333 317.8046 10953.55 259.954 | 1.091521 2.397213 -1.71181 -1.25098 |