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Table 6 For each top 3 pairwise pathway in BC basal: miRNA regulators of pathways, their expression levels in BC and in NS, and the statistical significance of the comparison (in terms of log Fold Change)

From: How interacting pathways are regulated by miRNAs in breast cancer subtypes

Pairwise pathways

miRNA-r

miRNA-r Exp. in BC

miRNA-r Exp. in NS

Statistical significance (log Fold Change)

1. a) Ethanol Degradation IV;

  b) Mismatch Repair in Eukaryotes

Hsa-miR-135b

342.0541

13.01149

4.96603

2. a) Putrescine Degradation III;

  b) Role of BRCA1 in DNA Damage Response

Hsa-miR-365-2

153.5541

506.0575

-1.39949

3. a) Tryptophan Degradation X (Mammalian, via Tryptamine);

  b) Role of BRCA1 in DNA Damage Response

Hsa-miR-365-2

153.5541

506.0575

-1.39949