Fig. 3

Transition-state diagram of HMM models. a TA model: Circles represent nodes (hidden states) and arrows signify transitions. Two models were constructed with either two or four states in the tail region. b SP model: Although globular region (1) and globular region (2) have different transitional states, their initial output probability conditions were identical. c MP model: Under the initial conditions, the output and transition probabilities of the SP, cap, and TMD regions were identical to those of the SP model. The loop region may comprise one to 20 residues