NEAT: an efficient network enrichment analysis test

BMC Bioinformatics

Table 1 An overview of simulations S1–S5

Simulation	Network type	Degree distribution	Graph density	Mean overlap	Maximum overlap
S1	Directed	Power law	3 %	4 %	11.3 %
S2	Directed	Mixture of 2 Poisson	4 %	3.6 %	9.5 %
S3	Directed	Mixture of 2 Poisson	4 %	–	–
S4	Undirected	Power law	3 %	3.8 %	12 %
S5	Undirected	Mixture of 2 Poisson	4 %	3.6 %	11 %

In Simulations S1 and S2, we compare the performance of NEAT in two directed networks with different degree distribution. In simulation S3, we check the performance of the test for different levels of overlap, ranging from 0 to 100 %. In Simulations S4 and S5, we compare NEAT to alternative tests in two undirected networks with different degree distribution

ISSN: 1471-2105