Table 3 Number of conserved orthologous interactions (COI) obtained by different network alignment algorithms

Yeast – Fly

Yeast – Worm

Yeast – Human

Yeast – Mouse

Fly – Worm

CUFID-align

91

10

743

5

3

SMETANA-CSRW

91

8

749

6

2

SMETANA

86

10

705

8

4

PINALOG

129

15

970

19

4

HubAlign

57

2

634

15

5

IsoRank

94

11

741

10

4

BLAST-MWBM

74

8

556

4

2

Fly – Human

Fly – Mouse

Worm – Mouse

Worm – Human

Human – Mouse

CUFID-align

202

13

1

21

111

SMETANA-CSRW

196

10

1

26

139

SMETANA

230

14

1

26

123

PINALOG

180

22

2

27

134

HubAlign

67

15

4

5

98

IsoRank

185

17

1

18

142

BLAST-MWBM

112

6

0

15

94