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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Improving sensitivity of linear regression-based cell type-specific differential expression deconvolution with per-gene vs. global significance threshold

Fig. 2

Parameters affecting sensitivity of cell type-specific differential expression detection. The effect of (a) per-group samples sizes (10, 14, and 18); (b) cell proportion SD (0.05, 0.1, and 0.15); (c) MSE (0.5, 1.5, and 2.5); (d) log2-transformation vs. as-is data. Unless specified otherwise, log2-transformed data was used, and the following parameters were held constant: per-group sample size - 14, condition number - 100, cell proportion SD - 0.1 (0.6 for C), MSE - 1.5

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BMC Bioinformatics

ISSN: 1471-2105

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