Improving sensitivity of linear regression-based cell type-specific differential expression deconvolution with per-gene vs. global significance threshold

Table 1 The number of cell type-specific differentially expressed probes (genes) identified in kidney transplant gene expression data from [5]

Cell	Neutrophils	Lymphocytes	Monocytes	Basophils	Eosinophils
Mean	0.592	0.281	0.098	0.025	0.004
SD	0.193	0.151	0.063	0.024	0.003
FDR < 0.3	0	0	1203 (882)	1	0
Bonferroni p-value < 0.05	3122	4975	9066 (6018)	648	1263
Overlapping	0	0	1187 (877)	0	0

Mean/SD – overall mean and standard deviation of a cell type-specific proportion

ISSN: 1471-2105