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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Tissue enrichment analysis for C. elegans genomics

Fig. 1

Schematic representation of trimming filters for an acyclical ontology. a The parent node (green) contains at least as many annotations as the union of the two sisters. These two sisters share annotations extensively, as expressed by the overlap in the Venn diagram, so they qualify for removal. b Nodes with less than a threshold number of genes are trimmed (red) and discarded from the dictionary. Here, the example threshold is 25 genes. Nodes ε,ζ,η, shown in red are removed. c Parent nodes are removed recursively, starting from the root, if all their daughter nodes have more than the threshold number of annotations. Nodes in grey (ε,ζ,η) were removed in the previous step. Nodes α,β shown in red are trimmed because each one has a complete daughter set. Only nodes γ and δ will be used to generate the static dictionary

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