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Table 2 Comparison of results for a GABAergic neuronal-enriched gene set from Watson [20] showing that results are similar regardless of annotation cutoff

From: Tissue enrichment analysis for C. elegans genomics

Tissue Q value33 Q value50 Enrichment fold change33 Enrichment fold change50
Nerve ring WBbt:0006749 0.005 0.0015 2.7 2.7
Nervous system WBbt:0005735 0.005 0.0015 1.4 1.4
Dorsal nerve cord WBbt:0006750 0.005 0.0015 3.8 3.8
Retrovesicular ganglion WBbt:0005656 0.011 0.0034 5 5
Ventral nerve cord WBbt:0005829 - 0.022 - 2.4
  1. We ran the same gene list on a dictionary with a minimum annotation cutoff of 50, similarity threshold of 0.95 and similarity method ‘any’ versus another with a minimum annotation cutoff of 33, similarity threshold of 0.95 and similarity method ‘any’. In the table, columns are labeled with their significance value (Q-value) or enrichment fold change followed by a hyphen and a number which indicates which the cutoff for the dictionary that was used for testing. Not all tissues are present in either dictionary. Hyphens denote not-applicable values, which occurs when a particular tissue is not present in both dictionaries