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Table 10 Best predicted functions by HMC-LMLP-Predicted

From: Reduction strategies for hierarchical multi-label classification in protein function prediction

Function

Description

01

Metabolism

01.01

Amino acid metabolism

01.03

Nucleotide/nucleoside/nucleobase metabolism

01.05

C-compound and carbohydrate metabolism

02

Energy

10

Cell Cycle and DNA processing

10.01

DNA processing

10.01.05

DNA recombination and DNA repair

10.01.05.01

DNA repair

10.03

Cell cycle

10.03.02

Meiosis

10.03.01.01.03

G1/S transition of mitotic cell cycle

11

Transcription

11.02

RNA synthesis

11.02.03.01

General transcription activities

11.04

RNA processing

11.04.01

rRNA processing

12

Protein Synthesis

12.01

Ribosome biogenesis

12.01.01

Ribosomal proteins

14

Protein fate (folding, modification, destination)

14.13.01.01

Proteasomal degradation (ubiquitin/proteasomal pathway)

16

Protein with binding function or cofactor requirement (structural or catalytic)

16.01

Protein binding

16.19

Nucleotide/nucleoside/nucleobase binding

20.01

Transported compounds (substrates)

20.01.01.01.01.01

Siderophore-iron transport

30

Cellular communication/Signal transduction mechanism

32

Cell rescue, defense and virulence

32.01

Stress response

34

Interaction with the cellular environment

34.11

Cellular sensing and response to external stimulus

34.11.03

Chemoperception and response

41

Development (Systemic)

42

Biogenesis of cellular components

43.01.03

Fungal and other eukaryotic cell type differentiation

43.01.03.05

Budding, cell polarity and filament formation