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Table 11 Worst predicted functions by HMC-LMLP-Predicted

From: Reduction strategies for hierarchical multi-label classification in protein function prediction

Function

Description

01.01.03.01.01

Biosynthesis of glutamine

01.01.03.03

Metabolism of proline

01.01.03.05

Metabolism of arginine

01.01.03.05.02

Degradation of arginine

01.01.05.01.01

Biosynthesis of polyamines

01.01.06.01

Metabolism of aspartate

01.01.06.01.01

Biosynthesis of aspartate

01.01.06.01.02

Degradation of aspartate

01.01.06.04

Metabolism of threonine

01.01.06.04.01

Biosynthesis of threonine

01.01.06.04.02

Degradation of threonine

01.01.09.01

Metabolism of glycine

01.01.09.01.02

Degradation of glycine

01.01.09.04.01

Biosynthesis of phenylalanine

01.01.09.05.01

Biosynthesis of tyrosine

01.01.11.01

Metabolism of alanine

01.01.11.02.02

Degradation of isoleucine

01.01.11.03.02

Degradation of valine

01.01.11.04

Metabolism of leucine

01.01.11.04.02

Degradation of leucine

01.02.02

Nitrogen metabolism

01.02.02.09

Catabolism of nitrogenous compounds

01.02.02.09.01

Urea catabolism (not urea cycle)

01.02.02.09.05

Cyanate catabolism

01.02.07

Regulation of nitrogen, sulfur and selenium metabolism

01.02.07.03

Regulation of sulphur metabolism

01.05.05

C-1 compound metabolism

01.05.05.04

C-1 compound anabolism

01.05.05.07

C-1 compound catabolism

01.20.05

Biosynthesismetabolism of acetic acid derivatives

01.20.05.09

Biosynthesismetabolism of eicosanoids

01.20.17.03

Biosynthesismetabolism of amines

01.20.19.05

Biosynthesismetabolism of cobalamins

01.20.31

Biosynthesismetabolism of secondary products derived from L-lysine, L-arginine and L-histidine

02.01.01

Glycolysis methylglyoxal bypass

02.16.03

Lactate fermentation

02.16.11

Propionate fermentation

16.06

Motor proteinmotor protein binding

20.03.02.02

Symporter

20.09.07.29

Vesicle recycling

30.05.01.10

Two-component signal transduction system (sensor kinase component)

32.07.05

Detoxification by export

34.07.02

Cell-matrix adhesion

38

Transposable Elements, viral and plasmid proteins

38.07

Proteins necessary for the integration or inhibition of transposon movement

40.01.03.01

Regulation of directional cell growth

40.10.02

Apoptosis (type I programmed cell death)

40.10.02.02

Apoptotic program

40.10.02.02.01

Apoptotic mitochondrial changes