TY - JOUR AU - Zhang, Xiao-Fei AU - Ou-Yang, Le AU - Dai, Dao-Qing AU - Wu, Meng-Yun AU - Zhu, Yuan AU - Yan, Hong PY - 2016 DA - 2016/09/09 TI - Comparative analysis of housekeeping and tissue-specific driver nodes in human protein interaction networks JO - BMC Bioinformatics SP - 358 VL - 17 IS - 1 AB - Several recent studies have used the Minimum Dominating Set (MDS) model to identify driver nodes, which provide the control of the underlying networks, in protein interaction networks. There may exist multiple MDS configurations in a given network, thus it is difficult to determine which one represents the real set of driver nodes. Because these previous studies only focus on static networks and ignore the contextual information on particular tissues, their findings could be insufficient or even be misleading. SN - 1471-2105 UR - https://doi.org/10.1186/s12859-016-1233-0 DO - 10.1186/s12859-016-1233-0 ID - Zhang2016 ER -