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Table 3 GO term enrichments for TS-MDS proteins and HK-MDS proteins

From: Comparative analysis of housekeeping and tissue-specific driver nodes in human protein interaction networks

 

TS-MDS

HK-MDS

Domains

GO terms

p-value

GO terms

p-value

BP

Cell-cell signaling

3.7E-05

Regulation of apoptosis

2.4E-18

 

Circulatory system process

4.8E-04

Regulation of programmed cell death

5.0E-18

 

Blood circulation

4.8E-04

Regulation of cell death

6.5E-18

 

Neuron projection development

6.5E-04

Protein transport

2.6E-17

 

Cell motion

8.2E-04

Protein modification by small protein conjugation

2.9E-17

CC

Plasma membrane part

2.9E-04

Cytosol

1.4E-44

 

Synapse

1.1E-03

Nuclear lumen

1.8E-40

 

Cell junction

1.3E-03

Organelle lumen

4.0E-38

 

Intrinsic to plasma membrane

2.6E-03

Membrane-enclosed lumen

3.0E-37

 

Integral to plasma membrane

5.0E-03

Intracellular organelle lumen

1.1E-36

MF

Sequence-specific DNA binding

5.1E-04

Transcription factor binding

1.7E-21

 

Transcription activator activity

3.3E-03

Identical protein binding

2.8E-20

 

Enzyme inhibitor activity

3.8E-03

Enzyme binding

2.2E-15

 

Transcription coactivator activity

5.1E-03

Small conjugating protein ligase activity

4.3E-14

 

Transcription factor activity

1.2E-02

Protein C-terminus binding

1.1E-12