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Table 3 Running time (seconds) for warm-start versus cold-started FVA in quad-precision using Quad MINOS (two LPs are run for each reaction)

From: solveME: fast and reliable solution of nonlinear ME models

Model Reactions Warm-start Cold-start Speed-up
E. coli ME (reduced) 16126 11.2 h >670 h 60 ×
T. maritima ME [3] 17535 78 h >1940 h 25×