Table 5 Orders of magnitude of ME reaction fluxes (in mmol/gDW/h). Based on aerobic glucose minimal medium simulation with feasibility and optimality tolerances of 10−20. Metabolic processes are categorized by subsystem [37]
From: solveME: fast and reliable solution of nonlinear ME models
Biological process | log10(v) min | log10(v) max | Median flux | Mean flux |
|---|---|---|---|---|
Transcription | –14 | –4 | 2.33E-6 | 6.46E-6 |
Complex formation | –14 | –4 | 4.92E-6 | 1.67E-5 |
Translation | –14 | –4 | 1.01E-5 | 2.18E-5 |
Cell Wall/Membrane/Envelope Metabolism | –7 | –7 | 1.78E-7 | 1.78E-7 |
tRNA charging | –7 | –1 | 0.0437 | 0.0559 |
Cofactor, Prosthetic Group and Folate Metabolism | –7 | 0 | 2.48E-5 | 0.0915 |
Amino Acid Metabolism | –6 | 1 | 0.159 | 0.679 |
Carbohydrate Metabolism | –5 | 1 | 2.48 | 2.74 |
Energy Production and Conversion | –1 | 1 | 5.82 | 11.5 |