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Fig. 26 | BMC Bioinformatics

Fig. 26

From: Subcellular protein expression models for microsatellite instability in colorectal adenocarcinoma tissue images

Fig. 26

DiSWOP results for comparing MSI and non-MSI sets of the simulated cancer samples at 40 × magnification. Different results are shown when comparing non-MSI samples to (a) both mutations, (b) MLH1 mutation only, and (c) MSH2 mutation only. Each node represents a protein and each edge colour shows a protein pair with different level of co-expression in the normal and cancer samples. Here, a large positive value (shown in red) indicates that the protein pair is more co-dependent in the mutated samples, whereas a large negative value (shown in blue) means that the protein pair is more active in non-MSI tissue

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