Fig. 3
From: Roar: detecting alternative polyadenylation with standard mRNA sequencing libraries
Example of read density and corresponding m/M values. a- Sashimi plot produced with IGV of two alignments for representative samples for testes and brain over the PRE and POST portions that we consider for CAMSAP1, one of the genes with the strongest shortening signal in testes versus brain. Read density is clearly lower in testes on the POST portion. CAMSAP1 is on the negative strand and the PRE fragment overlaps with the coding portion and the beginning of the 3’UTR of its last exon. b- Dot plot representing the m/M values obtained for the two testes and six brain samples. The larger m/M values for testes reflect the preferential expression of the short isoform in that tissue