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Fig. 9 | BMC Bioinformatics

Fig. 9

From: Convert your favorite protein modeling program into a mutation predictor: “MODICT”

Fig. 9

ROC curve. Trio groups (negative control, test, positive control) are tested for decreasing levels of stringency measured as a parameter depending on the standard deviation of the negative controls and the positive controls. There is a trade off between the p-value and the stringency. As stringency decreases, accuracy increases, however the increase in accuracy can be explained progressively less by the measurements of the algorithm (increasing p-value and decreasing significance). The data used to generate the above plot is indicated in Additional file 1: Table S1. The script for generating the data above is included in MODICT package

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