Convert your favorite protein modeling program into a mutation predictor: “MODICT”

BMC Bioinformatics

Table 2 Mutations in ACADM

Mutation pairs in ACADM with their residual enzyme activity and modict scores are listed. The values listed are expressed in percentages of residual enzyme activity with respect to wildtype enzyme activity. The residual enzyme activities are adapted from Sturm et. al., Fig. 11. modict scores are generated taking into account the main chain (26–421; Uniprot ID, ACADM_HUMAN; [51, 52]). Similar to Table 1, interpretation of these results are detailed in Fig. 5

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