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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Boolean regulatory network reconstruction using literature based knowledge with a genetic algorithm optimization method

Fig. 1

Optimization method. Our network optimization method takes as input a PKN and a training set and uses a genetic algorithm to find sub-graphs of the PKN which reproduce as well as possible all experiments in the training set. For each run of the optimization method, only the best network is kept as optimized network. To increase the chances to obtain good solutions, multiple independent runs of the optimization method are usually started in parallel, and only a fraction of optimized networks is kept as model networks

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BMC Bioinformatics

ISSN: 1471-2105

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