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Fig. 2 | BMC Bioinformatics

Fig. 2

From: TRIg: a robust alignment pipeline for non-regular T-cell receptor and immunoglobulin sequences

Fig. 2

Comparison of immune sequence alignments by different tools. Differences in length (x-axis) and identity (y-axis) of non-identical alignments by IgBLAST and TRIg (left column) and IMGT and TRIg (right column) for (a) our 454 data of human TRβ gene, (b) public Illumina data of human TRβ gene, and (c) public 454 data of mouse IgH gene. The differences were obtained by subtracting IgBLAST’s or IMGT’s values from TRIg’s values. Thus, dots in the first quadrant clearly indicate better alignments by TRIg. The validities of alignments in the second and fourth quadrants are less clear. However, for most dots in the two quadrants, TRIg’s annotations are more convincing because TRIg’s alignments are much longer or the identities much higher. Note that the dots may fall on top of each other, this explains the seemingly fewer dots than indicated in the first quadrant of (b)

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