Table 3 Enriched functional terms and canonical pathways, identified using DAVID and ingenuity pathway analysis (IPA)
Category | Term or pathway | P-value |
|---|---|---|
Promoter | ||
 SP_PIR_KEYWORDS | Transcription regulation | 2.00E-08 |
 GOTERM_MF | Transcription regulator activity | 6.72E-06 |
 GOTERM_BP | Regulation of transcription from RNA polymerase II promoter | 8.83E-06 |
 GOTERM_MF | Transcription factor activity | 2.56E-05 |
 SP_PIR_KEYWORDS | Phosphoprotein | 5.31E-05 |
 SP_PIR_KEYWORDS | DNA-binding | 9.99E-05 |
 GOTERM_BP | Regulation of RNA metabolic process | 1.31E-04 |
 GOTERM_BP | Positive regulation of transcription | 1.43E-04 |
 SP_PIR_KEYWORDS | Developmental protein | 1.56E-04 |
 SP_PIR_KEYWORDS | Activator | 1.85E-04 |
 SP_PIR_KEYWORDS | Repressor | 2.61E-04 |
 Canonical pathwaya | Role of NFAT in cardiac Hypertrophy | 4.36E-06 |
Wnt/β-catenin signalling | 2.42E-04 | |
Molecular Mechanisms of Cancer | 3.91E-04 | |
cAMP-mediated signalling | 5.60E-04 | |
Dopamine-DARPP32 Feedback in cAMP signalling | 6.05E-04 | |
Gene body | ||
 GOTERM_MF | DNA binding | 1.82E-07 |
 INTERPRO | IPR001766:Transcription factor, fork head | 3.34E-06 |
 GOTERM_MF | Sequence-specific DNA binding | 9.11E-06 |
 SP_PIR_KEYWORDS | Developmental protein | 9.66E-06 |
 GOTERM_MF | Transcription regulator activity | 4.65E-05 |
 GOTERM_MF | Transcription factor activity | 9.25E-05 |
 SP_PIR_KEYWORDS | Transcription regulation | 1.62E-04 |
 Canonical pathwaya | Notch signalling | 4.89E-05 |