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Table 2 All histone modifications considered in this study. The remaining histone modifications available from ENCODE are unsuitable for this study as they assert their functional role in non-promoter regions (e.g. H3K36me3 in the 3-UTR)

From: Distributed gene expression modelling for exploring variability in epigenetic function

Histone modification Regulatory role Chromatin localisation
H2A.Z Bivalency Euchromatin
H3K4me3 Activator/Bivalency Euchromatin
H3K9ac Activator Euchromatin
H3K9me3 Repressor Constitutive heterochromatin
H3K27ac Activator Euchromatin
H3K27me3 Repressor/Bivalency Facultative heterochromatin