Skip to main content
Fig. 4 | BMC Bioinformatics

Fig. 4

From: WUFlux: an open-source platform for 13C metabolic flux analysis of bacterial metabolism

Fig. 4

Carbon and energy distributions in both control and engineered E. coli strains. a carbon fates in the control strain; b carbon fates in the engineered strain; c ATP usage for biomass, fatty acids, and maintenance loss; d the influence of P/O ratios on SSR; e the influence of P/O ratios on flux calculation under ‘energy unbalanced’ conditions; and f the influence of P/O ratios on flux calculation under ‘energy balanced’ conditions. ‘Energy balanced’ represents the condition when the ATP maintenance loss is assumed as zero, and ‘energy unbalanced’ represents the condition when the ATP maintenance loss is unconstrained. The relative flux values in figures e and f are normalized to a glucose uptake rate of 100. Abbreviations for metabolites: 3PG, 3-phosphoglycerate; 6PG, 6-phosphogluconate; AceCoA, acetyl-CoA; AKG, α-ketoglutarate; F6P, fructose 6-phosphate; G6P, glucose 6-phosphate; GAP, glyceraldehyde 3-phosphate; GLX, glyoxylate; ICIT, isocitrate; PYR, pyruvate; and SUC, succinate

Back to article page