Symbol | definition |
---|---|
A | The adjacency matrix of disease similarity network |
G i | The adjacency matrix of the tissue-specific molecular network of |
disease i (for NoN) | |
G i∗ | The adjacency matrix of the center molecular network of disease i |
(for NoSN) | |
G ip | The adjacency matrix of the p th auxiliary molecular network of |
disease i (for NoSN) | |
I n | An n×n identity matrix |
r i | The ranking score vector of genes in G i (for NoN) |
e i | The seed vector of genes in G i (for NoN) |
r i∗ | The ranking score vector of genes in G i∗ (for NoSN) |
e i∗ | The seed vector of genes in G i∗ (for NoSN) |
r ip | The ranking score vector of genes in G ip (for NoSN) |
e ip | The seed vector of genes in G ip (for NoSN) |
h | Number of diseases in A |
n i | Number of genes in G i (for NoN) |
n i∗ | Number of genes in G i∗ (for NoSN) |
n ip | Number of genes in G ip (for NoSN) |
k i | Number of auxiliary molecular networks of disease i (for NoSN) |
d A (i) | Degree of disease i in A, i.e., \(d_{\mathbf {A}}(i) = \sum _{j=1}^{h}\mathbf {A}(i,j)\) |
\(\mathcal {I}_{ij}\) | The set of common genes in G i and G j (for NoN) |
\(\bar {\mathcal {I}}_{ij}\) | The set of genes in G i but not in G j (for NoN) |
\(\mathcal {I}_{i*,j*}\) | The set of common genes in G i∗ and G j∗ (for NoSN) |
\(\bar {\mathcal {I}}_{i*,j*}\) | The set of genes in G i∗ but not in G j∗ (for NoSN) |
\(\mathcal {I}_{i*,ip}\) | The set of common genes in G i∗ and G ip (for NoSN) |
\(\bar {\mathcal {I}}_{i*,ip}\) | The set of genes in G i∗ but not in G ip (for NoSN) |