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Table 1 Summary of symbols

From: Disease gene prioritization by integrating tissue-specific molecular networks using a robust multi-network model

Symbol

definition

A

The adjacency matrix of disease similarity network

G i

The adjacency matrix of the tissue-specific molecular network of

 

disease i (for NoN)

G i∗

The adjacency matrix of the center molecular network of disease i

 

(for NoSN)

G ip

The adjacency matrix of the p th auxiliary molecular network of

 

disease i (for NoSN)

I n

An n×n identity matrix

r i

The ranking score vector of genes in G i (for NoN)

e i

The seed vector of genes in G i (for NoN)

r i∗

The ranking score vector of genes in G i∗ (for NoSN)

e i∗

The seed vector of genes in G i∗ (for NoSN)

r ip

The ranking score vector of genes in G ip (for NoSN)

e ip

The seed vector of genes in G ip (for NoSN)

h

Number of diseases in A

n i

Number of genes in G i (for NoN)

n i∗

Number of genes in G i∗ (for NoSN)

n ip

Number of genes in G ip (for NoSN)

k i

Number of auxiliary molecular networks of disease i (for NoSN)

d A (i)

Degree of disease i in A, i.e., \(d_{\mathbf {A}}(i) = \sum _{j=1}^{h}\mathbf {A}(i,j)\)

\(\mathcal {I}_{ij}\)

The set of common genes in G i and G j (for NoN)

\(\bar {\mathcal {I}}_{ij}\)

The set of genes in G i but not in G j (for NoN)

\(\mathcal {I}_{i*,j*}\)

The set of common genes in G i∗ and G j∗ (for NoSN)

\(\bar {\mathcal {I}}_{i*,j*}\)

The set of genes in G i∗ but not in G j∗ (for NoSN)

\(\mathcal {I}_{i*,ip}\)

The set of common genes in G i∗ and G ip (for NoSN)

\(\bar {\mathcal {I}}_{i*,ip}\)

The set of genes in G i∗ but not in G ip (for NoSN)