A

The adjacency matrix of disease similarity network

G
_{
i
}

The adjacency matrix of the tissuespecific molecular network of


disease i (for NoN)

G
_{
i∗}

The adjacency matrix of the center molecular network of disease i


(for NoSN)

G
_{
ip
}

The adjacency matrix of the p
^{th} auxiliary molecular network of


disease i (for NoSN)

I
_{
n
}

An n×n identity matrix

r
_{
i
}

The ranking score vector of genes in G
_{
i
} (for NoN)

e
_{
i
}

The seed vector of genes in G
_{
i
} (for NoN)

r
_{
i∗}

The ranking score vector of genes in G
_{
i∗} (for NoSN)

e
_{
i∗}

The seed vector of genes in G
_{
i∗} (for NoSN)

r
_{
ip
}

The ranking score vector of genes in G
_{
ip
} (for NoSN)

e
_{
ip
}

The seed vector of genes in G
_{
ip
} (for NoSN)

h

Number of diseases in A

n
_{
i
}

Number of genes in G
_{
i
} (for NoN)

n
_{
i∗}

Number of genes in G
_{
i∗} (for NoSN)

n
_{
ip
}

Number of genes in G
_{
ip
} (for NoSN)

k
_{
i
}

Number of auxiliary molecular networks of disease i (for NoSN)

d
_{
A
}(i)

Degree of disease i in A, i.e., \(d_{\mathbf {A}}(i) = \sum _{j=1}^{h}\mathbf {A}(i,j)\)

\(\mathcal {I}_{ij}\)

The set of common genes in G
_{
i
} and G
_{
j
} (for NoN)

\(\bar {\mathcal {I}}_{ij}\)

The set of genes in G
_{
i
} but not in G
_{
j
} (for NoN)

\(\mathcal {I}_{i*,j*}\)

The set of common genes in G
_{
i∗} and G
_{
j∗} (for NoSN)

\(\bar {\mathcal {I}}_{i*,j*}\)

The set of genes in G
_{
i∗} but not in G
_{
j∗} (for NoSN)

\(\mathcal {I}_{i*,ip}\)

The set of common genes in G
_{
i∗} and G
_{
ip
} (for NoSN)

\(\bar {\mathcal {I}}_{i*,ip}\)

The set of genes in G
_{
i∗} but not in G
_{
ip
} (for NoSN)
