TY - JOUR AU - Song, Yang AU - Cai, Weidong AU - Huang, Heng AU - Feng, Dagan AU - Wang, Yue AU - Chen, Mei PY - 2016 DA - 2016/11/16 TI - Bioimage classification with subcategory discriminant transform of high dimensional visual descriptors JO - BMC Bioinformatics SP - 465 VL - 17 IS - 1 AB - Bioimage classification is a fundamental problem for many important biological studies that require accurate cell phenotype recognition, subcellular localization, and histopathological classification. In this paper, we present a new bioimage classification method that can be generally applicable to a wide variety of classification problems. We propose to use a high-dimensional multi-modal descriptor that combines multiple texture features. We also design a novel subcategory discriminant transform (SDT) algorithm to further enhance the discriminative power of descriptors by learning convolution kernels to reduce the within-class variation and increase the between-class difference. SN - 1471-2105 UR - https://doi.org/10.1186/s12859-016-1318-9 DO - 10.1186/s12859-016-1318-9 ID - Song2016 ER -