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Fig. 1 | BMC Bioinformatics

Fig. 1

From: SABRE: a method for assessing the stability of gene modules in complex tissues and subject populations

Fig. 1

Visual derivation of the H-index. A visual depiction of the derivation of the H-index is shown for modules identified by the WGCNA algorithm. A set of reference modules derived from all available samples are compared to a series of comparator module sets derived from bootstrapped re-sampled data. For each re-sampled dataset, all reference modules are compared to all newly identified modules using the Jaccard similarity coefficient. For each reference module, the best match Jaccard similarity coefficient value is recorded. Finally, these best match similarity coefficients are sorted and a measure of the area under the resulting curve (Hirsch-index) used to estimate the reference module’s stability

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