Fig. 2From: Global inference of disease-causing single nucleotide variants from exome sequencing dataResults on simulation studies based on sequencing data from 1000 Genome Project. For each region, results on simulation studies are summarized as four metrics: (1) the number of neutral variants; (2) TOP, the number of causal variants ranked in top 10; (3) MRR, the average rank ratio of causal variants; (4) AUC, the average area under the rank ROC. Regions are categorized into a Exon; b Promoter; c Intron; d Splice site. The x axis denotes different populations. Population abbreviations: ASW, people with African ancestry in Southwest United States; CEU, Utah residents with ancestry from Northern and Western Europe; CHB, Han Chinese in Beijing, China; CHS, Han Chinese South, China; CLM, Colombiansin Medellin, Colombia; FIN, Finnish in Finland; GBR, British from England and Scotland, UK; IBS, Iberian populations in Spain; LWK, Luhya in Webuye, Kenya; JPT, Japanese in Tokyo, Japan; MXL, people with Mexican ancestry in Los Angeles, California; PUR, Puerto Ricans in Puerto Rico; TSI, Toscani in Italia; YRI, Yoruba in Ibadan, Nigeria. Ancestry-based groups: AFR, African; AMR, Americas; EAS, East Asian; EUR, EuropeanBack to article page