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Table 2 Silhouette Scores obtained using the transformed expression values from top 15% variance genes on applying different preprocessing techniques (using first three principal components)

From: GFS: fuzzy preprocessing for effective gene expression analysis

  Raw Scaled Z-Score Quantile GFS
ALL (9 subtypes) -0.212 -0.209 -0.145 -0.099 0.312
ALL (2 subtypes) 0.009 0.027 0.043 0.070 0.145
DMD 0.025 0.044 0.096 0.202 0.203
Leukemia 0.153 0.128 0.177 0.227 0.289
  1. Silhouette scores corresponding to GFS are the highest among all methods (highlighted in bold)