Table 2 The rare driver genes in HNSC
Rank | Gene | Cases with mutations | Mutation frequency (%) | p-value | CGC gene |
|---|---|---|---|---|---|
14 | AKT1 | 10 | 1.996008 | 0.011832 | YES |
15 | RB1 | 9 | 1.796407 | 0.012938 | YES |
18 | CALM1 | 7 | 1.397206 | 0.016769 | NO |
22 | MAPK1 | 4 | 0.798403 | 0.019237 | NO |
23 | PLCG1 | 5 | 0.998004 | 0.030388 | YES |
24 | ZBTB16 | 8 | 1.596806 | 0.032729 | YES |
30 | SETDB1 | 3 | 0.598802 | 0.044476 | NO |
32 | PTK2 | 4 | 0.798403 | 0.048264 | NO |