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Table 3 Predictive performance of structural features for the four benchmark datasets

From: Prediction of HIV-1 protease cleavage site using a combination of sequence, structural, and physicochemical features

Features

DT

LR

ANN

Acc.(%)

AUC

Acc.(%)

AUC

Acc.(%)

AUC

746 Dataset

 SSE

62.1

0.626

59.4

0.715

78.3

0.838

 SA

83.7

0.791

78.4

0.771

81.0

0.771

 Str_All

83.7

0.791

70.2

0.806

78.4

0.897 *

1625 Dataset

 SSE

81.7

0.756

76.8

0.673

85.3

0.742

 SA

91.4

0.920

89.0

0.961

96.3

0.977

 Str_All

91.5

0.920

85.4

0.936

89.0

0.935

Schilling Dataset

 SSE

87.1

0.500

88.3

0.775

88.3

0.800

 SA

89.5

0.788

84.0

0.828

87.1

0.840

 Str_All

89.5

0.788

83.4

0.824

85.8

0.843

Impens Dataset

 SSE

85.1

0.500

85.1

0.729

87.2

0.761

 SA

89.3

0.736

89.3

0.918

95.7

0.950

 Str_All

87.2

0.571

89.3

0.857

89.3

0.914

  1. *The best accuracy and AUC in each dataset are underlined