Skip to main content

Table 6 Predictive performance based on selected features and machine learning algorithms based on validation sets and test sets

From: Prediction of HIV-1 protease cleavage site using a combination of sequence, structural, and physicochemical features

Datasets

Features

Algorithm

Sen.(%)

Spe.(%)

Acc.(%)

AUC

746

Seq + Str

ANN

100.0 (100.0)*

88.2 (94.4)

94.5 (97.4)

0.994 (0.995)

1625

Seq + Str

ANN

94.7 (89.4)

95.2 (96.8)

95.1 (95.1)

0.992 (0.994)

Schilling

Seq + Str + Phy

ANN

57.1 (27.3)

96.5 (95.8)

91.4 (86.6)

0.895 (0.815)

Impens

SA

ANN

71.4 (44.4)

100.0 (89.8)

95.7 (80.0)

0.950 (0.816)

  1. *The predictive performance of test set is shown in parenthesis