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Table 5 Performance comparison of SVM-PSSM on the ATP168 dataset with different definitions of ligand binding sites

From: Protein ligand-specific binding residue predictions by an ensemble classifier

Definitiona

Accuracy (%)

Sensitivity (%)

Specificity (%)

MCC

LPC

96.00

33.40

99.28

0.47

BioLip

95.14

22.34

98.10

0.24

  1. aBinding sites were defined using the LPC and BioLip databases, respectively